r-Retinoate Day & Night 50ml

The most advanced retinoid in Medik8's range — and one of the most sophisticated OTC anti-ageing products available anywhere. r-Retinoate Day & Night uses retinyl retinoate, a next-generation vitamin A ester that delivers retinoid activity through an alternative receptor pathway to traditional retinol or retinaldehyde. The result is comparable anti-ageing efficacy with dramatically less irritation — making it suitable for even the most sensitive skin types.

What it does:

• Reduces fine lines, wrinkles, and loss of firmness through dual vitamin A pathways
• Improves skin texture, tone, and overall radiance from 2–4 weeks
• Photostable formula — safe for both AM and PM use (always with SPF in the morning)
• No tolerance-building phase required — effective from the first application
• Suitable for sensitive skin that cannot tolerate Crystal Retinal or clinically reviewed retinoid

Best for: Patients who want premium retinoid results without irritation. Ideal for sensitive or reactive skin types, retinoid-intolerant patients, or anyone seeking the convenience of a twice-daily retinoid. Also excellent as a complement to in-clinic treatments.

How to use: Apply a small amount to clean skin morning and evening. In the AM, follow with vitamin C serum (optional) and SPF. In the PM, follow with a hydrating night moisturiser. Can be used from day one without a build-up phase.