Obagi Medical
Obagi CLENZIderm M.D. System
Obagi CLENZIderm M.D. System
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A comprehensive three-step acne treatment system clinically proven to clear acne at the source. The CLENZIderm M.D. System combines a foaming cleanser, pore therapy toner, and 5% benzoyl peroxide therapeutic lotion to address all stages of acne formation — from excess sebum and pore congestion to bacterial proliferation.
Unlike standard benzoyl peroxide washes, CLENZIderm uses a patented solubilised BPO that penetrates into the follicle where C. acnes bacteria live — not just the surface. This is what makes it significantly more effective than off-the-shelf acne products.
Clinical Results:
- 87% of patients reported the system was effective or very effective
- 81% satisfied or very satisfied with their acne improvement at week 12
- Results seen as early as week 1, with continued improvement through 12 weeks
- Early and continuous reduction in acne breakouts demonstrated in clinical studies
The system includes:
- Daily Care Foaming Cleanser — 2% salicylic acid removes excess oil and dissolves pore blockages
- Pore Therapy — solubilised BPO toner that penetrates into the follicle to kill acne-causing bacteria
- Therapeutic Lotion — 5% benzoyl peroxide formula for sustained antibacterial action
Best for:
- Mild to moderate acne requiring a targeted, multi-step protocol
- Persistent breakouts unresponsive to over-the-counter spot treatments
- Those seeking a clinician-recommended acne system with proven results
Clinician tip: For best results, pair with cosmeceutical retinoid (available via consultation) and a lightweight hydrator to maintain barrier function. Purchase the full CLENZIderm + cosmeceutical retinoid + Hydrator + SPF protocol and receive 10% off your entire order.
Clinician's Note
Clinician's Note
This product has been personally reviewed and selected by our founder based on clinical evidence, ingredient efficacy, and real-world patient outcomes. If you're unsure whether this is right for your skin, start a free written skin assessment and we'll recommend the best option for you.
How to Use
How to Use
Apply as directed by the product packaging or your clinician's recommendation. For best results, use consistently as part of a complete skincare routine. Not sure about application order? Ask our clinician — it's free.
Shipping & Returns
Shipping & Returns
Dispatch: 1-2 working days
Delivery: 2-4 working days (Royal Mail tracked)
Free shipping on orders over £100
Returns: Unused, unopened products may be returned within 7 days with prior approval. Prescription items cannot be returned once dispensed.
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Complete Your Acne Protocol
BPO can be drying — pair with lightweight hydration and SPF to keep skin balanced while clearing breakouts.


